The Clinical Reality: Do Vertical Mice Reduce Carpal Tunnel Pressure?
Key Research Findings
- Clinical Efficacy: Current peer-reviewed literature indicates that vertical mice do not significantly reduce intracarpal canal pressure compared to standard mice.
- The Trade-off: While vertical mice reduce ulnar deviation (sideways bending), they often induce compensatory wrist extension (bending back), which neutralizes the benefits.
- Activity vs. Posture: The dynamic activity of using the mouse (clicking/moving) elevates nerve pressure significantly more than the static posture of the hand.
The vertical mouse is frequently marketed as a therapeutic intervention for Carpal Tunnel Syndrome (CTS). The prevailing marketing narrative suggests that neutralizing forearm pronation (rotating the hand to a "handshake" position) will inherently reduce Carpal tunnel pressure.
However, evidence-based ergonomic practice requires that we distinguish between theoretical benefits and measured clinical outcomes. This report reviews two seminal studies—Schmid et al. (2015) and Keir et al. (1999)—to evaluate these claims rigorously.
Study 1: Evidence on Ergonomic Devices for CTS Patients
Source: Schmid AB, et al. "A vertical mouse and ergonomic mouse pads alter wrist position but do not reduce carpal tunnel pressure in patients with carpal tunnel syndrome." Applied Ergonomics. 2015.

The Findings on Pressure
“In fact, the pressure with the vertical mouse and gliding palm support was marginally higher compared to a standard mouse... Thus, based on the findings of this study, wrist pads and the vertical mouse cannot be recommended for patients with CTS over a standard mouse if reduction of carpal tunnel pressure is the main criterion.”
If the medical goal is to lower pressure inside the carpal tunnel, this study found that vertical mice failed to achieve this. In some cases, pressure was actually slightly higher. Clinical data does not support the claim that vertical mice are inherently "safer" for the median nerve.
The Mechanism: The "Extension" Trade-Off
“The potential benefit of a neutral forearm position... may have been neutralised by a more extended wrist position, which was prominent in this condition.”
Ergonomics is often a trade-off. While the vertical mouse fixed ulnar deviation (sideways bending), it caused users to bend their wrists backward (extension). This new strain cancelled out the benefits of the "neutral" handshake position.
Study 2: Evidence on Posture vs. Activity
Source: Keir PJ, Bach JM, Rempel D. "Effects of computer mouse design and task on carpal tunnel pressure." Ergonomics. 1999.
The Impact of Forearm Rotation (Pronation)
“Mousing, in general, promotes a fully pronated forearm... However, it appears that there is relatively little effect of pronation in the range tested.”
This finding challenges the core marketing claim of vertical mice. The data indicates that rotating the arm from "palm down" to "handshake" causes minimal difference in actual carpal tunnel pressure. The body tolerates forearm rotation relatively well.
The Impact of Task Activity
“There was, however, a significant increase in carpal tunnel pressure when using the mouse as opposed to resting the hand on the mouse (i.e. static posture).”
The significant risk factor was the activity of the hand, not just the position. The moment the user begins to click and move, pressure spikes. The effort of use is a more critical variable than the angle of the wrist.
Conclusion
Based on rigorous data, the vertical mouse presents a biomechanical paradox. While it visually aligns the forearm, this does not translate into a significant reduction of intracarpal pressure. The failure stems from compensatory wrist extension and the fact that task-related exertion overrides postural benefits.
A Note from Dr. Sig: Our Research Philosophy
Are we saying vertical mice never work? No.
We acknowledge that for many users, changing any posture can provide relief by shifting the load to different muscles. However, we are rigorously debunking the pseudoscientific marketing claims that mislead consumers. We believe you deserve to choose tools based on verifiable data, not empty promises.
Read the Full Vertical Mouse Investigation
- Part 1: The Bone Myth (X-Ray Analysis)
- Part 2: The Clinical Review (Pressure Data) (Current Post)
- Part 3: The Pinch Force Risk (Biomechanics)
- Part 4: Performance (Aim Stability)
References
(1) Schmid AB, et al. (2015). "A vertical mouse... do not reduce carpal tunnel pressure." Applied Ergonomics. Source
(2) Keir PJ, et al. (1999). "Effects of computer mouse design and task on carpal tunnel pressure." Ergonomics. Source
0 comments